Linda Berg Luecke receives CTSI TL1 Fellowship!

May 2019

Linda Berg Luecke, a 2nd year graduate student in the MSTP program, received a 1-year renewable fellowship from the Clinical & Translational Science Institute (CTSI) Training Program (TL1). The award includes a monthly stipend, travel funds, and tuition. Her project will focus on defining the molecular features of a cell surface protein she discovered in cardiac fibroblasts from heart failure patients.

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Chris Ashwood Publishes Innovative Glycomics Method in Analyst!

May 2019

In this collaborative manuscript with the Packer lab, we combined the use of hydrolyzed dextran as an internal standard and Skyline software for post-acquisition normalization to reduce retention time and peak area technical variation in PGC-based glycan analyses. This strategy was designed to facilitate the implementation of PGC-based separations in glycomics studies by providing a strategy to develop system-independent retention values to normalize technical variation.

https://www.ncbi.nlm.nih.gov/pubmed/31065629

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New Rigorous Protocol for Assessing Cardiomyocyte Identity

January 2019

In this manuscript, we demonstrate pitfalls with popular antibodies and sample preparation conditions commonly used for the assessment of cardiomyocyte identity within differentiation cultures. By using a rigorous fit-for-purpose workflow, the authors developed and validated a comprehensive protocol to accurately assess cardiomyocyte identity within hPSC-CM cultures. The new protocol includes stepwise instructions to facilitate its implementation by experts and novices, alike.

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